Immunity to melanoma: unraveling the relation of tumor immunity and autoimmunity
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چکیده
منابع مشابه
Using Autoimmunity To Inform Tumor Immunity.
s of unpublished, original research are presented during Poster Sessions and Block Symposia (oral presentations of poster data). This is perhaps the most dynamic aspect of the AAI annual meeting. Take part in face-to-face discussions with abstract authors and learn about their most recent, unpublished research. Poster Sessions will be held daily (unopposed by any other sessions) in the Exhibit ...
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Self-antigens, in the form of differentiation antigens, are commonly recognized by the immune system on melanoma and other cancers. We have shown previously that active immunization of mice against the melanocyte differentiation antigen, a tyrosinase-related protein (TRP) gp75(TRP-1) (the brown locus protein) expressed by melanomas, could induce tumor immunity and autoimmunity manifested as dep...
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The immune system can recognize self antigens expressed by cancer cells. Differentiation antigens are prototypes of these self antigens, being expressed by cancer cells and their normal cell counterparts. The tyrosinase family proteins are well characterized differentiation antigens recognized by antibodies and T cells of patients with melanoma. However, immune tolerance may prevent immunity di...
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ژورنال
عنوان ژورنال: Oncogene
سال: 2003
ISSN: 0950-9232,1476-5594
DOI: 10.1038/sj.onc.1206462